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Sent on Tuesday, 2009 Dec 22Search kinetoplastids OR kinetoplastid OR Kinetoplastida OR "trypanosoma brucei" OR leishmania OR brucei OR leishmaniasis OR "African trypanosomiasis"
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| PubMed Results |
| 1. | Vet Parasitol. 2009 Dec 1. [Epub ahead of print]Fleas and ticks as vectors of Leishmania spp. to dogs: Caution is needed.Otranto D, Dantas-Torres F.Dipartimento di Sanità Pubblica e Zootecnia, Università degli Studi di Bari, Valenzano, Bari, Italy. |
| PMID: 20022429 [PubMed - as supplied by publisher] | |
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| 2. | Dev World Bioeth. 2009 Dec;9(3):157-160.LEISHMANIASIS ENTOMOLOGICAL FIELD STUDIES: ETHICAL ISSUES.Andrade-Narvaez F, Canto-Lara SB, Del Rosario Garcia-Miss M.Foro Latinoamericano de Comités de Etica en Investigación para la Salud, FLACEIS/SIDCER/TDR/WHO. Occupational health remains neglected in developing countries because of competing social, economic and political challenges. Ethical issues in the workplace related to the hazards and risks of becoming infected by Leishmania (Leishmania) mexicana, through the bite of naturally infected sand flies, is another area of concern that has been neglected as well. We report here the results of reviewing two entomological field studies carried out in our research center from 2003 to 2006. Eight students from our School of Biology were invited to catch sand flies. A total of six of the eight (75%) developed a typical clinical picture of Localized Cutaneous Leishmaniasis (LCL) caused by L. (L.) mexicana. In this article we identify the ethical issues related to these kinds of studies and propose some guidelines for conducting them. |
| PMID: 20021495 [PubMed - as supplied by publisher] | |
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| 3. | J Parasitol. 2009 Dec 18:1. [Epub ahead of print]PREVALENCE OF ANTIBODIES TO TRYPANOSOMA CRUZI, LEISHMANIA INFANTUM, ENCEPHALITOZOON CUNICULI, SARCOCYSTIS NEURONA, AND NEOSPORA CANINUM AND IN CAPYBARA, HYDROCHOERUS HYDROCHAERIS, FROM SAO PAULO STATE BRAZIL.Valadas S, Gennari S, Yai L, Rosypal A, Lindsay D.Little is known about the importance of capybara, Hydrochoerus hydrochaeris, as reservoirs for parasites of zoonotic or veterinary importance. Sera from 63 capybaras from 6 counties in the state of São Paulo, Brazil were examined for antibodies to Trypanosoma cruzi, Leishmania infantum, Encephalitozoon cuniculi, Sarcocystis neurona, and Neospora caninum using an indirect immunofluorescent antibody test. Five (8%) of the 63 capybaras had antibodies to T. cruzi epimastigotes. None of the samples from capybara reacted positively with L. infantum promastigotes or spores of E. cuniculi. Two (3%) of the serum samples were positive for antibodies to S. neurona merozoites and 2 (3%) of the serum samples were positive for antibodies to N. caninum tachyzoites. A serum sample from 1 capybara was positive for antibodies to both T. cruzi and N. caninum. None of the remaining 62 samples reacted with more than 1 parasite. |
| PMID: 20020808 [PubMed - as supplied by publisher] | |
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| 4. | Curr Opin Immunol. 2009 Aug;21(4):385-90. Epub 2009 Jul 29.CD8+ T cells in Trypanosoma cruzi infection.Padilla AM, Bustamante JM, Tarleton RL.Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA. CD8(+) T cells have emerged as crucial players in the control of a number of protozoan pathogens, including Trypanosoma cruzi, the agent of human Chagas disease. The recent identification of the dominant targets of T. cruzi-specific T cells has allowed investigators to follow the generation of and document the functionality of T cell responses in both mice and humans. Although slow to develop in the early stages of the infection, T. cruzi-specific CD8(+) T cells reach prodigious levels and remain highly functional throughout chronic infections in mice. Following drug-induced cure during either the acute or chronic stage, these immunodominant T cells persist as stable, antigen-independent memory populations. T. cruzi-specific CD8(+) T cells in humans are less-well-studied but appear to lose functionality and decline in numbers in these decades-long infections. Changes in the frequency of parasite-specific T cell upon therapeutic treatment in humans may provide a new metric for determining treatment efficacy. PMCID: PMC2735075 [Available on 2010/8/1] |
| PMID: 19646853 [PubMed - indexed for MEDLINE] | |
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